Pathognomonic Signs

Disease	Sign
Addison's disease	Bronze-like skin
Angina pectoris	Levine's sign (hand clutching of chest)
Bulimia Nervosa	Chipmunk facies (parotid gland swelling)
Cholecystitis	Murphy's sign (pain on deep inspiration when inflamed gallbladder is palpated)
Cholera	Rice-watery stool
Chronic hemorrhagic pancreatitis	Grey-Turner's sign (ecchymosis in flank area)
Cushing syndrome	Moon face
Diphtheria	Pseudomembrane on tonsils, pharynx and nasal cavity
Duchenne's Muscular Dystrophy	Gowers' sign
Emphysema	Barrel chest
Hyperthyroidism	Exophthalmos
Hypocalcemia	Trousseau sign and Chvostek sign
Kawasaki Disease	Strawberry tongue
Liver cirrhosis	Spider angioma
Leprosy	Leonine facies (thickened lion-like facial skin)
Measles	Koplik's spots
Meningitis	Kernig's sign and Brudzinski's sign
Pancreatitis	Cullen's sign (bluish discoloration of umbilicus)
Parkinson’s disease	Pill-rolling tremors
Patent ductus arteriosus	Machine-like murmur
Pernicious anemia	Red beefy tongue
Systemic Lupus Erythematosus	Butterfly rash
Tetanus	Risus sardonicus
Typhoid fever	Rose spots in abdomen

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